- gene. It is a
member of the nicotinamide-nucleotide
adenylyltransferases (
NMNATs)
which catalyze nicotinamide adenine dinucleotide (NAD) synthesis. The coenzyme...
-
pathways such as MAP
kinase and
inducing axonal loss and
neuronal death.
NMNAT is an
enzyme with
neurorescuing properties that
functions to
deplete NMN...
- In enzymology, nicotinamide-nucleotide
adenylyltransferase (
NMNAT) (EC 2.7.7.1) are
enzymes that
catalyzes the
chemical reaction ATP +
nicotinamide mononucleotide...
- gene
product belongs to the nicotinamide-nucleotide
adenylyltransferase (
NMNAT)
enzyme family,
members of
which catalyze an
essential step in the nicotinamide...
- PMID 21550379.
Coleman MP,
Freeman MR (2010). "Wallerian degeneration, wld(s), and
nmnat". Annu Rev Neurosci. 33: 245–67. doi:10.1146/annurev-neuro-060909-153248...
-
isoforms of nicotinamide-nucleotide
adenylyltransferase (
NMNAT)
found in humans. As with the
other NMNATs, NMNAT3 is an
enzyme that
catalyzes nicotinamide adenine...
-
helps to
explain the
protective nature of the
survival factor NMNAT2, as
NMNAT enzymes have been
shown to
prevent SARM1-mediated
depletion of NAD+. This...
- NAD+ production. NMN is then
converted to NAD+ by NMN-adenylyltransferase (
NMNAT).
Research in
mammals indicates that NRK1 is a
cytosolic protein, encoded...
-
Coleman MP,
Freeman MR (1 June 2010). "Wallerian degeneration, wld(s), and
nmnat".
Annual Review of Neuroscience. 33 (1): 245–67. doi:10.1146/annurev-neuro-060909-153248...
-
decreased the
levels of the
nicotinamide mononucleotide adenylyltransferase (
Nmnat)
proteins Nma1 and Nma2. NATs
belongs to the GCN5
related N-acetyltransferases...
