-
phosphorodiamidate morpholino oligomer),
especially in
medical literature. Vivo-
Morpholinos and PPMO are
modified forms of
Morpholinos with
chemical groups...
- 2-morpholinoethanesulfonic acid; 2-(4-
morpholino)ethanesulfonic acid; 2-(N-
morpholino)ethanesulfonic acid; 2-(4-
morpholino)ethanesulfonic acid; MES; MES hydrate;...
- and
antisense oligonucleotides for
Morpholinos targeting other exons are also
subsequently approved.
Morpholinos have been used in
preclinical studies...
- MOPS (3-(N-
morpholino)propanesulfonic acid) is a
buffer introduced in the 1960s, one of the
twenty Good's buffers. It is a
structural analog to MES, and...
-
fragments of
analogs of
nucleic acids such as
peptide nucleic acid or
Morpholinos. The
units of an
oligomer may be
connected by
covalent bonds,
which may...
- N-Nonanoylmorpholine, 1-(4-
Morpholino)-1-nonanone, 4-Morpholinenonylic acid,
Pelargonic acid morpholide,
Pelargonic morpholide, N-
Morpholino nonanamide,...
- Prof.
Janet Heasman's
earlier work with
Morpholinos in
Xenopus embryos, led to
rapid adoption of
Morpholino technology by the
developmental biology community...
-
backbone sugar.
These analogues include locked nucleic acids (LNA),
morpholinos and
peptide nucleic acids (PNA). In sequencing,
dideoxynucleotides are...
- (snRNPs) to pre-mRNA
using Morpholino antisense oligos. This has
become a
standard technique in
developmental biology.
Morpholino oligos can also be targeted...
- needed] Aptamers,
oligonucleotides with
important biological applications Morpholinos,
oligos with non-natural backbones,
which do not
activate RNase-H but...
