- 5,10-
Methenyltetrahydrofolate (5,10-CH=THF) is a form of
tetrahydrofolate that is an
intermediate in metabolism. 5,10-CH=THF is a
coenzyme that accepts...
- 10-
methenyltetrahydrofolate: CH2H4F + NAD+ ⇌ {\displaystyle \rightleftharpoons } CH2H2F + NADH + H+ In the
second step 5,10-
methenyltetrahydrofolate undergoes...
- enzymology, a
methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) is an
enzyme that
catalyzes the
chemical reaction 5,10-
methenyltetrahydrofolate + H2O ⇌ {\displaystyle...
- GS,
Demirbas D,
Laine R, Yang E, et al. (September 2018). "5,10-
methenyltetrahydrofolate synthetase deficiency causes a
neurometabolic disorder ****ociated...
- transformylase,
glycinamide ribonucleotide transformylase, GAR TFase, 5,10-
methenyltetrahydrofolate:2-amino-N-ribosylacetamide
ribonucleotide transformylase Databases...
- activities,
methylenetetrahydrofolate dehydrogenase (1.5.1.5),
methenyltetrahydrofolate cyclohydrolase (3.5.4.9) and formate–tetrahydrofolate
ligase (6...
- form),
methyltetrahydrofolate (the
primary form
found in blood),
methenyltetrahydrofolate,
folinic acid, folacin, and
pteroylglutamic acid.
Historic names...
- 5,10-
Methenyltetrahydrofolate synthetase deficiency (MTHFS deficiency) is a rare
neurodevelopmental disorder caused by
mutations affecting the
MTHFS gene...
-
converts to 5-methyltetrahydrofolate, 5-formyltetrahydrofolate, and
methenyltetrahydrofolate. It is
substrate for the
enzyme methylenetetrahydrofolate reductase...
-
Dihydropteridine reductase deficiency - in up to 25% of
patients 5,10-
methenyltetrahydrofolate synthetase deficiency Holoprosencephaly Primary microcephaly Wiedemann-Steiner...
