-
Kisspeptins (including
kisspeptin-54 (KP-54),
formerly known as metastin) are
proteins encoded by the KISS1 gene in humans.
Kisspeptins are
ligands of...
- of the
kisspeptin receptor is
linked to the
phospholipase C and
inositol trisphosphate second messenger cascades inside the cell.
Kisspeptins are neuropeptides...
- PMID 24008670. Navarro, VM (2013). "Interactions
Between Kisspeptins and
Neurokinin B".
Kisspeptin Signaling in
Reproductive Biology.
Advances in Experimental...
- GnRH release,
kisspeptin indirectly promotes the
secretion of LH and FSH from the
pituitary gland. Two main po****tions of
kisspeptin neurons have been...
-
Kisspeptin,
neurokinin B, and
dynorphin (KNDy)
neurons are
neurons in the
hypothalamus of the
brain that are
central to the
hormonal control of reproduction...
- IGF-2)
Agonists Kisspeptin (
kisspeptin-54, metastin)
Kisspeptin-10 KISS1-305 MVT-602 (RVT-602, TAK-448) TAK-683
Antagonists Kisspeptin-234
Agonists Leptin...
-
hypogonadism (nHH)
hypothalamic hypogonadism olfacto-genital
syndrome Kisspeptin is a
protein that
regulates the
release of GnRH from the hypothalamus...
- females;
dopamine may
inhibit LH
release in
ovariectomized females.
Kisspeptin appears to be an
important regulator of GnRH release. GnRH
release can...
- pre-pubertal
growth and a
significant delay in
puberty onset.
Mutations in the
kisspeptin (KISS1) and its receptor, KISS1R (also
known as GPR54),
involved in GnRH...
-
hypothesized that
neurokinin B
might play a role in
regulating the
secretion of
kisspeptin, a
compound responsible for
triggering direct release of GnRH as well...
