-
Retroviral integrase (IN) is an
enzyme produced by a
retrovirus (such as HIV) that
integrates (forms
covalent links between) its
genetic information into...
-
Integrase inhibitors (INIs) are a
class of
antiretroviral drug
designed to
block the
action of
integrase, a
viral enzyme that
inserts the
viral genome...
- (backwards). The new DNA is then
incorporated into the host cell
genome by an
integrase enzyme, at
which point the
retroviral DNA is
referred to as a provirus...
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usually identical, but
there are
exceptions (e.g. attP and attB of λ
integrase).
Based on
amino acid
sequence homologies and
mechanistic relatedness...
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version of its
genome into the host cell DNA is
called its "
integrase". HIV-1
integrase catalyzes the “cut-and-paste”
action of
clipping the host DNA...
- to NNRTIs.
Integrase inhibitors (also
known as
integrase nuclear strand transfer inhibitors or INSTIs)
inhibit the
viral enzyme integrase,
which is responsible...
- cell
nucleus and
integrated into the
cellular DNA by a
virally encoded integrase and host co-factors. Once integrated, the
virus may
become latent, allowing...
-
specific recombination events. The
enzyme (38 kDa) is a
member of the
integrase family of site
specific recombinase and it is
known to
catalyse the site...
- (insufflation), a
method of
administrating some
medications and
vaccines Integrase, a
retroviral enzyme In (album), by the Outsiders, 1967 In (Korean name)...
-
endowed with an RT (reverse-transcriptase) and an
RNAse H domains, and an
integrase (IN). Typically, LTR-retrotransposon
mRNAs are
produced by the host RNA...
