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Indoleamine-pyrrole 2,3-dioxygenase (IDO or INDO EC 1.13.11.52) is a heme-containing
enzyme physiologically expressed in a
number of
tissues and cells...
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Indolamines are a
family of
neurotransmitters that
share a
common molecular structure (namely, indolamine).
Indolamines are a
classification of monoamine...
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Indoleamine 2,3-dioxygenase 2 (IDO2) is a
protein that in
humans is
encoded by the IDO2 gene. IDO2 (indolamine-2,3-dioxygenase) is an
enzyme with protein...
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tryptophan oxygenase and L-tryptophan pyrrolase) and the
closely related indoleamine 2,3-dioxygenase
enzyme (IDO). Both TDO and IDO
contain one noncovalently...
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immunomodulating and
antineoplastic activities.
Linrodostat is an
inhibitor of
indoleamine 2,3-dioxygenase 1 (IDO1).
Linrodostat has
entered clinical trials for...
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chemical compound that is an
inhibitor of the
tryptophan catabolic enzyme indoleamine 2,3-dioxygenase (IDO or INDO EC 1.13.11.52). It is a
chiral compound...
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arthritis under the
brand name Olumiant. As of 2016 epacadostat, an
indoleamine 2,3-dioxygenase (IDO1) inhibitor, was in
development for
various cancers...
- is an
investigational drug for cancer.
Epacadostat is an
inhibitor of
indoleamine 2,3-dioxygenase-1 (IDO1).
Epacadostat inhibits IDO1 by competitively...
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tryptophan is
mainly (more than 95%) metabolized. Two enzymes,
namely indoleamine 2,3-dioxygenase (IDO) in the
immune system and the brain, and tryptophan...
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Aeruginascin or N,N,N-trimethyl-4-phosphoryloxytryptamine is an
indoleamine derivative which occurs naturally within the
mushrooms Inocybe aeruginascens...
