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Orexin (/ɒˈrɛksɪn/), also
known as
hypocretin, is a
neuropeptide that
regulates arousal, wakefulness, and appetite. It
exists in the
forms of orexin-A...
- chemical-drug
methods involve hypocretin treatments methods such as ****ure
drugs like
hypocretin agonists (such as danavorexton) or
hypocretin replacement, in the...
-
autoimmune destruction of
hypothalamic neurons that
produce the
neuropeptide hypocretin (also
called orexin),
which regulates arousal and has a role in stabilization...
- The
orexin receptor (also
referred to as the
hypocretin receptor) is a G-protein-coupled
receptor that
binds the
neuropeptide orexin.
There are two variants...
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Orexin receptor type 1 (Ox1R or OX1), also
known as
hypocretin receptor type 1 (HcrtR1), is a
protein that in
humans is
encoded by the HCRTR1 gene. The...
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Orexin receptor type 2 (Ox2R or OX2), also
known as
hypocretin receptor type 2 (HcrtR2), is a
protein that in
humans is
encoded by the HCRTR2 gene. The...
-
Jennings KJ, de
Lecea L (2019). "
Hypocretins (Orexins):
Twenty Years of
Dissecting Arousal Circuits". The Orexin/
Hypocretin System:
Functional Roles and Therapeutic...
- Orexin-A, also
known as
hypocretin-1, is a
naturally occurring neuropeptide and
orexin isoform. The
orexinergic nucleus in the
lateral hypothalamus is...
-
catabolic effects have been discovered,
including cytokines,
orexin (known as
hypocretin), and melatonin.[citation needed] The word
catabolism is from Neo-Latin...
- brain.
Another key
system is that
provided by the
orexins (also
known as
hypocretins)
projecting neurons.
These exist in
areas adjacent to
histamine neurons...
