- 5-
Hydroxymethylcytosine (5hmC) is a DNA
pyrimidine nitrogen base
derived from cytosine. It is
potentially important in epigenetics,
because the hydroxymethyl...
- the
discovery of a new
mammalian DNA
modification 5-
hydroxymethylcytosine. 5-
Hydroxymethylcytosine converts to cytosine-5-methylsulfonate upon bisulfite...
- DNA
methyltransferase or be
methylated and
hydroxylated to make 5-
hydroxymethylcytosine. The
difference in
rates of
deamination of
cytosine and 5-methylcytosine...
-
enzymes catalyze the
hydroxylation of DNA 5-methylcytosine (5mC) to 5-
hydroxymethylcytosine (5hmC), and can
further catalyse oxidation of 5hmC to 5-formylcytosine...
- to the
invention of TAB-seq, a
biochemical method that can map 5-
hydroxymethylcytosine (5hmC) at base-resolution genome-wide, as well as hmC-Seal, a method...
-
modifications include adenine methylation in bacteria, the
presence of 5-
hydroxymethylcytosine in the brain, and the
glycosylation of
uracil to
produce the "J-base"...
-
Nucleobase 5,6-Dihydrouracil 5-Methylcytosine 5-
Hydroxymethylcytosine Nucleoside Dihydrouridine D 5-Methylcytidine m5C Pseudouridine...
-
primordial germ cells. The
erasure of 5mC
occurs via its
conversion to 5-
hydroxymethylcytosine (5hmC)
driven by high
levels of the ten-eleven
dioxygenase enzymes...
- TET3
enzyme facilitates conversion of 5-methylcytosine (5mC) to 5-
hydroxymethylcytosine (5hmC),
initiating active DNA demethylation, an
epigenetic mechanism...
- that
carry out
oxidative reactions (e.g. 5-methylcytosine to 5-
hydroxymethylcytosine) and
enzymes of the DNA base
excision repair (BER) pathway. At different...
