-
produced from the NRG1 gene by
alternative splicing.
These isoforms include heregulins (HRGs),
glial growth factors (GGFs) and
sensory and
motor neuron-derived...
- as the
formation of
neuromuscular synapses.
Included in the
family are
heregulin; neu
differentiation factor;
acetylcholine receptor synthesis stimulator;...
-
transforming growth factor α (TGF-α),
transforming growth factor β (TGF-β),
heregulin, Wnt, RANKL, and
leukemia inhibitory factor (LIF).
These factors regulate...
-
Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists:
Neuregulins (
heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Duligotumab Patritumab Seribantumab...
- the
protein for dimerization. ErbB3 has been
shown to bind the
ligands heregulin and NRG-2.
Ligand binding causes a
change in
conformation that allows...
-
Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists:
Neuregulins (
heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Duligotumab Patritumab Seribantumab...
-
Lapatinib Mubritinib Neratinib Tucatinib ErbB3/HER3 Agonists:
Neuregulins (
heregulins) (1, 2, 6 (neuroglycan C)) Antibodies:
Duligotumab Patritumab Seribantumab...
- 1994). "Solution
structure of the
epidermal growth factor-like
domain of
heregulin-alpha, a
ligand for p180erbB-4". EMBO J. 13 (15): 3517–23. doi:10.1002/j...
- Y, Yu WH, Ren J, Chen W,
Huang L,
Kharbanda S, et al. (August 2003). "
Heregulin targets gamma-catenin to the
nucleolus by a
mechanism dependent on the...
-
Bispecific Antibody That
Targets the ErbB2/ErbB3
Oncogenic Unit and
Inhibits Heregulin-Induced
Activation of ErbB3.
Molecular Cancer Therapeutics OpenWorm Downloads...
