-
Glucuronidation is
often involved in drug
metabolism of
substances such as drugs, pollutants, bilirubin, androgens, estrogens, mineralocorticoids, glucocorticoids...
-
hydroxyl groups. This
linkage process is
known as
glucuronidation (or
glucuronide conjugation).
Glucuronidation occurs mainly in the liver,
although the enzymes...
- via a
glycosidic bond. The
glucuronides belong to the glycosides.
Glucuronidation, the
conversion of
chemical compounds to glucuronides, is a method...
- of UDP-glucuronic acid to a
small hydrophobic molecule. This is a
glucuronidation reaction.
Alternative names:
glucuronyltransferase UDP-glucuronyl transferase...
- CYP2D6 and CYP2C9 via
aromatic ring
oxidation and
glucuronidation, then
further conjugated by
glucuronidation and sulfation. The
three active metabolites exhibit...
-
glucuronosyltransferase (UDP-glucuronosyltransferase,
UDPGT or UGT), an
enzyme of the
glucuronidation pathway that
transforms small lipophilic (fat-soluble) molecules, such...
-
epicatechin metabolites (SREM). The main
metabolic pathways for
SREMs are
glucuronidation,
sulfation and
methylation of the
catechol group by catechol-O-methyl...
- body. The bilirubin-UGT
enzyme performs a
chemical reaction called glucuronidation.
Glucuronic acid is
transferred to
unconjugated bilirubin,
which is...
- PMID 19039354.
Liston HL,
Markowitz JS,
DeVane CL (October 2001). "Drug
glucuronidation in
clinical psychopharmacology". J Clin Psychopharmacol. 21 (5): 500–15...
- irinotecan, is
activated by
hydrolysis to SN-38, and is then
inactivated by
glucuronidation by
uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1). The inhibition...
