-
Frataxin is a
protein that in
humans is
encoded by the FXN gene. It is
located in the
mitochondrion and
Frataxin mRNA is
mostly expressed in
tissues with...
- gene on
chromosome 9,
which makes a
protein called frataxin. In FRDA,
cells produce less
frataxin.
Degeneration of
nerve tissue in the
spinal cord causes...
- an
expanded repeat sequence GAA in the
frataxin gene. The
frataxin gene is
responsible for
producing the
frataxin protein,
which is a
mitochondrial protein...
- forms.[citation needed]
Sphingolipids have also been
implicated with the
frataxin protein (Fxn), the
deficiency of
which is ****ociated with Friedreich's...
- In
molecular biology, the
frataxin-like
domain is a
protein domain found in
proteins including eukaryotic frataxin and
bacterial CyaY. The
bacterial CyaY...
-
subunit alpha. In addition,
PMPCB has been
shown to
interact with
PMPCA and
Frataxin. The
majority of
mitochondrial proteins is nuclear-coded,
which necessitates...
- they do
display proteins required for Fe–S
cluster biosynthesis (like
frataxin,
cysteine desulfurase, Isu1 and a
mitochondrial Hsp70). Additionally, modified...
-
pathway facilitating proton movement away from the
catalytic histidine.
Frataxin chaperones iron to the
matrix side of ferrochelatase,
where aspartate and...
-
shown to
interrupt transcription of the X25, or
frataxin gene. As
decreased levels of the
protein frataxin is ****ociated with Friedreich's ataxia, formation...
-
Evidences showed that MPP was
involved in the
proteolytic maturation of
Frataxin, a
protein responsible for iron homeostasis. Accordingly, MPP deficiency...
