-
Methoxy arachidonyl fluorophosphonate,
commonly referred as MAFP, is an
irreversible active site-directed
enzyme inhibitor that
inhibits nearly all serine...
- (nucleophilic substitution). This
compound is then
reacted with a
phosgene oxime-like
chloride to open the ring and
create the
product fluorophosphonate....
- have carbon-phosphorus or nitrogen-phosphorus bonds. The
organic fluorophosphonates react with
serine esterases and
serine proteases irreversibly. This...
- aldehydes, haloalkanes, alkenes,
Michael acceptors,
phenyl sulfonates, or
fluorophosphonates.
These electrophilic groups react with
amino acid side
chains to form...
- TL-466 ATC code S01EB07 (WHO)
Identifiers IUPAC name bis(propan-2-yl)
fluorophosphonate CAS
Number 55-91-4 Y
PubChem CID 5936
DrugBank DB00677 Y ChemSpider...
-
Fluorophosphonate-rhodamine (FP-Rhodamine) activity-based
probe for
profiling of the
serine hydrolase superfamily. In this
probe the fluorophosphonate...
-
serine enzymes.
AEBSF DFP (diisopropyl fluorophosphate), an
analogous fluorophosphonate phosphorylating reagent Das, Amit K.; Bellizzi, John J.; Tandel, Sagun;...
- regulation. PMSF DFP (diisopropyl fluorophosphate), an
analogous fluorophosphonate phosphorylating reagent "Pefabloc® SC" (PDF). Pentapharm. Retrieved...
- identified.
Orlistat (tetrahydrolipstatin; THL) and
methyl arachidonyl fluorophosphonate (MAFP), so-called "universal lipase/serine
hydrolase inhibitors" that...
- the
reporter tag is used to
enrich or
detect the
labeled protein.
Fluorophosphonate-biotin is an
example of an activity-based
probe that
targets serine...
