-
Epothilones are a
class of
potential cancer drugs. Like taxanes, they
prevent cancer cells from
dividing by
interfering with tubulin, but in
early trials...
- It was
approved for use in
China in 2021.
Utidelone is a
member of the
epothilone class of
natural products,
which are
metabolites produced by the soil-dwelling...
- denticulata,
zaragozic acid A, a
potent inhibitor of
sterol synthesis, and
epothilone A and B,
which have been
proven to be very
effective anticancer drugs...
-
Sagopilone is a
fully synthetic macrolide of the
epothilone family with the
molecular formula C30H41NO6S. The
mechanism of
action is
similar to taxanes...
-
synthesis of
polyketide natural products and
drugs such as
Oseltamivir and
Epothilone.
Aldol reactions Kohlpainter, Christian; Schulte, Markus; Falbe, Jürgen;...
-
antigen (PSMA) and has also developed, with Bristol-Myers Squibb, an
epothilone-folic acid
conjugate (BMS-753493),
described at a 2008 conference. In...
- benzothiazoles. In
addition to
vitamin B1, the
thiazole ring is
found in
epothilone.
Other important thiazole derivatives are benzothiazoles, for example...
-
resulting in apoptosis.
Epothilone A and
epothilone B
exhibit both
antifungal and
cytotoxic properties.
These epothilones are
competitive inhibitors...
- than most alternatives.
Chiral pool
synthesis is used to
build a part of
epothilone (an
alternative to pa****axel) from
readily available enantiopure (–)-pantolactone...
-
Gramicidin Zwittermicin A
Antibiotic precursors ACV-Tripeptide
Cytostatics Epothilone Fabclavine Bleomycin Immunosuppressants Ciclosporin (Cyclosporine A) Siderop****s...
