-
Epipodophyllotoxins are
substances naturally occurring in the root of
American Mayapple plant (Podophyllum peltatum). Some
epipodophyllotoxin derivatives...
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Pharmacological Basis of Therapeutics, chapter: 61.
Cytotoxic agents/
Epipodophyllotoxins Twelfth Edition ISBN 978-0-07-162442-8 Lewis, W.H. and M.P.F. Elvin-Lewis...
-
during the
period of 1970 to 1990,
including anthracyclines and
epipodophyllotoxins — both of
which inhibited the
action of
topoisomerase II, an enzyme...
- malignant; Etoposide: a
topoisomerase inhibitor from the
group of
epipodophyllotoxins; Prednisolone: a
glucocorticoid hormone that can
cause apoptosis...
-
which may
include AML-M5, has been ****ociated with
exposure to
epipodophyllotoxins, such as etoposide. Many
cases of AML-M5 are seen to have enhanced...
-
individuals treated with
certain types of chemotherapy, such as
epipodophyllotoxins and cyclophosphamide.
There is some
evidence that a
common infection...
- h.
Excretion Kidney and
fecal Identifiers IUPAC name 4'-Demethyl-
epipodophyllotoxin 9-[4,6-O-(R)-ethylidene-beta-D-glucopyranoside], 4' -(dihydrogen phosphate)...
- well as a
reduced drug ac****ulation
effect tumor cell
resistance to
epipodophyllotoxins and anthracyclines. It has been
proposed that the
level of TopII...
-
Etoposide (Fig. 7) and its
close relative teniposide (VM-26) are
epipodophyllotoxin derivatives obtained from the
rhizome of wild
mandrake that target...
- malignancies,
radiation therapy,
alkylating antineoplastic agents, and
epipodophyllotoxins are not used, and
methotrexate can be used only with caution; the...