- In enzymology, a
dihydropyrimidine dehydrogenase (NADP+) (EC 1.3.1.2) is an
enzyme that
catalyzes the
chemical reaction 5,6-dihydrouracil + NADP+ ⇌ {\displaystyle...
-
Dihydropyrimidine dehydrogenase deficiency is an
autosomal recessive metabolic disorder in
which there is
absent or
significantly decreased activity of...
- J.; Malley, M. F. (1992). "
Dihydropyrimidine calcium channel blockers. 4.
Basic 3-substituted-4-aryl-1,4-
dihydropyrimidine-5-carboxylic acid esters. Potent...
- may also
induce more
severe diarrhoea by
means of this synergy. The
dihydropyrimidine dehydrogenase (DPD)
enzyme is
responsible for the
detoxifying metabolism...
-
fluorouracil induced stomatitis through use of
allopurinol mouthwash. The
dihydropyrimidine dehydrogenase (DPD)
enzyme is
responsible for the
detoxifying metabolism...
-
Depressive personality disorder,
disorder with
depressive features Dihydropyrimidine dehydrogenase, an
enzyme N,N-diethyl-p-phenylenediamine, a phenylenediamine...
- in
cyclic amides. The
systematic name of this
enzyme class is 5,6-
dihydropyrimidine amidohydrolase.
Other names in
common use
include hydantoinase, hydropyrimidine...
-
oteracil or uracil.
These agents achieve this by
inhibiting the
enzyme dihydropyrimidine dehydrogenase (uracil/gimeracil) or
orotate phosphoribosyltransferase...
-
Other names in
common use
include dehydrogenase, dihydrouracil,
dihydropyrimidine dehydrogenase,
dihydrothymine dehydrogenase,
pyrimidine reductase...
-
normally administered intravenously to
prevent its
degradation by
dihydropyrimidine dehydrogenase in the gut wall.
Doxifluridine is a fluoropyrimidine...
