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Desmosterol (Cholesta-5,24-dien-3β-ol) is a
lipid present in the
membrane of
phytoplankton and an
intermediate product in
cholesterol synthesis in mammal...
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decreased significantly.
Clomifene is an
inhibitor of the
conversion of
desmosterol into
cholesterol by the
enzyme 24-dehydrocholesterol reductase. Concerns...
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conversion of
desmosterol into cholesterol.
Although effective in
reducing cholesterol levels, this
results in
tissue ac****ulation of
desmosterol,
which in...
- (24R,24′R)-fucosterol
epoxide ⇌ {\displaystyle \rightleftharpoons }
desmosterol +
acetaldehyde This
enzyme belongs to the
family of lyases, specifically...
-
azacosterol and
triparanol inhibit the
production of
cholesterol from
desmosterol, one of the last
steps in
cholesterol biosynthesis, and were formerly...
- to cholesterol, as well as the
reduction of 7-dehydrodesmosterol to
desmosterol. It
requires NADPH as a
cofactor for this reduction, and may involve...
- 24-dehydrocholesterol
reductase (24-DHCR),
preventing the
formation of
cholesterol from
desmosterol.
Although it
primarily acts to
inhibit 24-DHCR, the drug also inhibits...
-
defect in
cholesterol biosynthesis. It
results in an ac****ulation of
desmosterol and a
variety of ****ociated symptoms. Only two
cases have been reported...
- determined. ABCG4 has demonstrated, in vitro, to parti****te in the
efflux of
desmosterol and amyloid-β
peptide (Aβ). It is
highly expressed in the brain, but...
-
lathosterol sterol metabolic process cholesterol biosynthetic process via
desmosterol steroid biosynthetic process cholesterol biosynthetic process xenobiotic...
