Definition of Defactinib. Meaning of Defactinib. Synonyms of Defactinib

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Definition of Defactinib

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Meaning of Defactinib from wikipedia

- Avutometinib/defactinib, sold under the brand name Avmapki Fakzynja Co-Pack, is a co-packaged medication used for the treatment of ovarian cancer. It contains...
- Defactinib (INN, codenamed VS-6063) is an inhibitor of PTK2, also known as focal adhesion kinase (FAK), Pyk2, and MELK which was developed by Pfizer and...
- in 2020 for clinical trials. The co-packaged medication avutometinib/defactinib was approved for medical use in the United States in May 2025. Ishii N...
- Infigratinib Pemigatinib Avapritinib Cabozantinib Capivasertib Capmatinib Defactinib (+avutometinib) Entrectinib Gilteritinib Larotrectinib Lenvatinib Masitinib...
- officer (CEO) of Verastem Oncology. Their leading investigational drug is defactinib (VS-6063), is a small-molecule focal adhesion kinase (FAK) inhibitor designed...
- Infigratinib Pemigatinib Avapritinib Cabozantinib Capivasertib Capmatinib Defactinib (+avutometinib) Entrectinib Gilteritinib Larotrectinib Lenvatinib Masitinib...
- clinical trials in 2014 were: VS-6062 (PF 562,271), VS-6063 (PF-04554878 defactinib) and VS-4718 (PND-1186) (all three are ATP-competitive kinase inhibitors)...