- C-type
lectin domain family 7
member A or
Dectin-1 is a
protein that in
humans is
encoded by the CLEC7A gene. CLEC7A is a
member of the C-type lectin/C-type...
-
Dectin-2 or C-type
lectin domain containing 6A is a
protein that in
humans is
encoded by the CLEC6A gene.
Dectin-2 is a
member of the C-type lectin/C-type...
-
glucose units connected by β-1,3-glycosidic linkages. It
binds to TLR 2 and
Dectin-1 (CLEC7A).
Zymosan is a
ligand found on the
surface of fungi, like yeast...
- or
plasma origin. Non-opsonic
receptors include lectin-type receptors,
Dectin receptor, or
scavenger receptors. Some
phagocytic pathways require a second...
-
among the TLR-dependent signaling. TLR-independent
signaling such as
Dectin 1, and
Dectin 2 –
mincle signaling lead to MAP
kinase and NFkB activation. Membrane...
- motifs,
which have a very
similar structure and
function (for
example in
Dectin-1 protein).
ITAMs are
important for
signal transduction,
mainly in immune...
- and 2 as well as
Dectin-1 to
activate the
phosphoinositide 3-kinase
pathway in
order to
express the anti-inflammatory genes.
Dectin-1
binds to the fungal...
- CG,
Ansems M,
Brossart P,
Wright MD,
Adema GJ, et al. (January 2007). "
Dectin-1
interaction with
tetraspanin CD37
inhibits IL-6 production".
Journal of...
-
adaptive immune system myelocyte immune system C-type
lectin receptors (CLR) (
Dectin 1, Mincle) CARD9/BCL10/MALT1
complex → NF-κB
innate immune system...
-
macrophages activated through a
specific inflammatory pathway activated by the
Dectin-1
receptor are
capable of
promoting axon recovery, also
however causing...
