-
Alkylation is a
chemical reaction that
entails transfer of an
alkyl group. The
alkyl group may be
transferred as an
alkyl carbocation, a free radical,...
- (2RNH2 → R2NH + NH3). And finally,
quaternary ammonium salts can be
dealkylated using ethanolamine: R4N+ + NH2CH2CH2OH → R3N + RN+H2CH2CH2OH Aminonaphthalenes...
- properties. The
other metabolites identified include a N-
dealkylated metabolite, and an O-
dealkylated 1/16
metabolite with a
plasma half-life of 59 hours....
-
methylcobalamin for use as cofactors. That is,
methylcobalamin is
first dealkylated and then regenerated.
According to one author, it is
important to treat...
-
available and is a
strong Lewis acid. It is an
excellent demethylating or
dealkylating agent for the
cleavage of ethers, also with
subsequent cyclization, often...
- of administration. It is
absorbed slowly into the plasma.
Macitentan dealkylates into the
active metabolite aprocitentan (ACT-132577),
which reaches its...
- compounds. JWH-018 and its N-
dealkylated metabolite were only
detected in
small amounts, with
hydroxylated N-
dealkylated metabolites comprising the primary...
- for half an hour to
three hours.
Lidocaine is
about 95%
metabolized (
dealkylated) in the
liver mainly by CYP3A4 to the
pharmacologically active metabolites...
-
chemical compounds. They can be used to form
protecting groups and as N-
dealkylating agents. They are
listed as
extremely hazardous substances. 'A new reagent...
- oxidation, and
degradation of the ethyl‐bridge
yielding the O/N‐bis‐
dealkylated metabolite,
combinations thereof and
further glucuronidation or sulfations...
