-
utilization proteins, the
histone deacetylases form an
ancient protein superfamily known as the
histone deacetylase superfamily. HDACs, are classified...
- A
protein deacetylase is any
enzyme that
removes acetyl groups from
lysine amino acids in proteins. The main ones are
histone deacetylases (HDACs) and...
-
Histone deacetylase inhibitors (HDAC inhibitors, HDACi, HDIs) are
chemical compounds that
inhibit histone deacetylases.
Since deacetylation of histones...
- and Leu144. This gene
product belongs to the
histone deacetylase family.
Histone deacetylases act via the
formation of
large multiprotein complexes and...
-
Schreiber SL (April 1999). "Three
proteins define a
class of
human histone deacetylases related to
yeast Hda1p".
Proceedings of the
National Academy of Sciences...
- t(8;21) in
acute leukemia,
makes distinct contacts with
multiple histone deacetylases and
binds mSin3A
through its
oligomerization domain".
Molecular and Cellular...
- In enzymology, an
acetylspermidine deacetylase (EC 3.5.1.48) is an
enzyme that
catalyzes the
chemical reaction N8-acetylspermidine + H2O ⇌{\displaystyle...
- Sano H,
Adachi K, Miwa T (1997). "Purification and
properties of two
deacetylases produced by
Vibrio alginolyticus H-8". Biosci. Biotechnol. Biochem. 61:...
- Sir2 and some, but not all,
sirtuins are
protein deacetylases.
Unlike other known protein deacetylases,
which simply hydrolyze acetyl-lysine residues,...
- KM,
Bouriotis V (September 2005). "Peptidoglycan N-acetylglucosamine
deacetylases from
Bacillus cereus,
highly conserved proteins in
Bacillus anthracis"...