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Samuel J.
Danishefsky (born
March 10, 1936) is an
American chemist working as a
professor at both
Columbia University and the
Memorial Sloan-Kettering...
- The
Danishefsky Taxol total synthesis in
organic chemistry is an
important third Taxol synthesis published by the
group of
Samuel Danishefsky in 1996...
- Synthesis. 2008 (3): 409–412. doi:10.1055/s-2008-1032023. Lambert, T. H.;
Danishefsky, S. J. (2006). "Total
Synthesis of UCS1025A".
Journal of the American...
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Danishefsky's diene (Kitahara diene) is an
organosilicon compound and a
diene with the
formal name trans-1-methoxy-3-trimethylsilyloxy-buta-1,3-diene...
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diene is 1-methoxy-3-trimethylsiloxy-buta-1,3-diene,
otherwise known as
Danishefsky's diene. It has
particular synthetic utility as
means of
furnishing α...
- reaction,
reacting with a wide
variety of dienes. In one example, a
Danishefsky-type
diene is
reacted with a
cyclopentenone to
yield a
fused tricyclic...
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below is an
excerpt of the
synthesis of an
analogue of
Mitomycin C by
Danishefsky. The
exchange of a
protecting group from a
methyl ether to a MOM-ether...
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iodolactonization as a key step in
obtaining the
desired product. In 1977,
Samuel Danishefsky and
coworkers were able to
synthesize the
tumor growth inhibitors dl-vernolepin...
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organic synthesis, for
example in
desulfonylation reactions; annulation;
Danishefsky, Kuwajima,
Mukaiyama and
Holton Taxol total syntheses;
strychnine total...
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ability to
access complex molecules of
varying ring sizes. In 2003,
Danishefsky and
others reported the
total synthesis of (+)-migrastatin, a macrolide...
