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Samuel J.
Danishefsky (born
March 10, 1936) is an
American chemist working as a
professor at both
Columbia University and the
Memorial Sloan-Kettering...
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Danishefsky's diene (Kitahara diene) is an
organosilicon compound and a
diene with the
formal name trans-1-methoxy-3-trimethylsilyloxy-buta-1,3-diene...
- The
Danishefsky Taxol total synthesis in
organic chemistry is an
important third Taxol synthesis published by the
group of
Samuel Danishefsky in 1996...
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diene is 1-methoxy-3-trimethylsiloxy-buta-1,3-diene,
otherwise known as
Danishefsky's diene. It has
particular synthetic utility as
means of
furnishing α...
- Synthesis. 2008 (3): 409–412. doi:10.1055/s-2008-1032023. Lambert, T. H.;
Danishefsky, S. J. (2006). "Total
Synthesis of UCS1025A".
Journal of the American...
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activity but
simpler to produce. The
concept was
introduced by
Samuel J.
Danishefsky in 2006.
Notable examples of this
strategy are the
potential drug ixabepilone...
- VCH
Verlagsgesellschaft mbH, 1987, S. 179, ISBN 3-527-25991-0.
Samuel Danishefsky;
Takeshi Kitahara & Paul F.
Schuda (1983). "Preparation and Diels-Alder...
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tolerates the
presence of
carbamate and
ether substituents.
Samuel J.
Danishefsky's synthesis of both (+) and (-)
peribysin began with a Saegusa–Ito oxidation...
- latter-day
examples of
syntheses include Wender's, Holton's, Nicolaou's, and
Danishefsky's total syntheses of the anti-cancer drug pa****axel (trade name Taxol)...
- (3): 317–318. doi:10.1093/oxfordjournals.jbchem.a122464. PMID 3071527.
Danishefsky AT,
Onnufer JJ,
Petsko GA,
Ringe D (February 1991). "Activity and structure...
