-
Chordin (from Gr**** χορδή, string, catgut) is a
protein with a
prominent role in dorsal–ventral
patterning during early embryonic development. In humans...
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Chordin-like 1 is a
protein that in
humans is
encoded by the CHRDL1 gene.
Chordin-Like 1 (CHRDL1) is a
structural glycoprotein that sits on the X chromosome...
- as the
organizer of the organizer. Even with the BCNE
center (Blastula
chordin and
noggin expression center)
removed from the blastula, the Nieuwkoop...
- pathways.
Activation of
various secreted factors (Vg1, Nodal, Wnt8C, FGF8 and
Chordin) and
transcription factors (Brachyury and Goosecoid)
adjacent to the site...
- domain-containing
protein (VWCE) Von
Willebrand factor (VWF)
Chordin (CHRD)
Chordin-like 1 (CHRDL1)
Chordin-like 2 (CHRDL2)
Brorin (VWC2) Collagen, type I, alpha...
-
investigations were able to
identify specific factors such as
noggin and
chordin as
genetic factors in the
dorsal lip that are
critical for
proper neural...
- streak. In the node proper, the
chordin expression pattern is very
similar to that of HNF-3b, but more rostrally,
chordin is no
longer expressed in the...
- non-neural tissue.
Examples of
neural inducers are the
molecules noggin and
chordin. When
embryonic ectodermal cells are
cultured at low
density in the absence...
- (non-neural) part of the
embryo while several sog-like BMP
inhibitors (
Chordin, Noggin, Follistatin) are
expressed dorsally.
Other patterning genes also...
- the
protein BMP4
appears to be involved. Two
proteins called Noggin and
Chordin, both
secreted by the mesoderm, are
capable of
inhibiting BMP4 and thereby...