- In enzymology, a
cholestenone 5alpha-reductase (EC 1.3.1.22) is an
enzyme that
catalyzes the
chemical reaction 5alpha-cholestan-3-one + NADP+ ⇌ {\displaystyle...
-
bromination to the
bromoketone and
elimination to the enone. The
conversion of
cholestenone into
cholesterol by the
method of
Dauben and
Eastham (1950) consisted...
-
Examples follow.
Cholesterol +
oxygen --(enzyme
cholesterol oxidase)-->
cholestenone +
hydrogen peroxide Hydrogen peroxide + 4-aminophenazone +
phenol --(enzyme...
- The
following reactions are
known to be
catalyzed by 5α-reductase:
Cholestenone → 5α-Cholestanone
Progesterone → 5α-Dihydroprogesterone 3α-Dihydroprogesterone...
- 3.1.3, 3-oxo-Δ4-steroid 5β-reductase,
androstenedione 5β-reductase,
cholestenone 5β-reductase,
cortisone 5β-reductase,
cortisone Δ4-5β-reductase, steroid...
-
function oxidoreductase activity,
acting on the CH-CH
group of
donors cholestenone 5-alpha-reductase
activity amide binding NADPH binding electron transfer...
- •
Simvastatin • STX-2171 • STX-2622 • STX-2624 5α-Reductase (SRD5A)
Cholestenone→5α-Cholestanone • Progesterone→5α-Dihydroprogesterone •...
- synthesis. The
reaction can be emplo**** in the
syntheses of
steroids such as
cholestenone, testosterone, and cortisone.
Below is a
scheme for the Fujimoto–Belleau...
-
acting on the CH-CH
group of
donors sterol 5-alpha
reductase activity cholestenone 5-alpha-reductase
activity amide binding oxidoreductase activity 3-oxo-5-alpha-steroid...
-
function oxidoreductase activity,
acting on the CH-CH
group of
donors cholestenone 5-alpha-reductase
activity oxidoreductase activity 3-oxo-5-alpha-steroid...
