-
Bryostatins are a
group of
macrolide lactones from (bacterial
symbionts of) the
marine organism Bugula neritina that were
first collected and provided...
-
since been used in the
synthesis of
several products,
particularly the
bryostatins. Evans–Tishchenko
reaction Saksena, Anil; Mangiaracina,
Pietro (1983)...
-
called bryostatins can be
extracted from the
marine bryozoan Bugula neritina. In 2001
pharmaceutical company GPC
Biotech licensed bryostatin 1 from Arizona...
- than was
previously achieved. For example,
total syntheses of roxaticin,
bryostatin and
cryptocaryol were
accomplished via
double Krische allylation of 1...
- myricitrin, gossypol.
Other PKCIs : Verbascoside, BIM-1, Ro31-8220.
Bryostatin 1 can act as a PKC inhibitor; It was
investigated for cancer. Tamoxifen...
-
discovery that
Bryostatin-1 can be used to
treat latent HIV
infection and
formed the
basis for
clinical trials on the use of
Bryostatin as a
latent infection-reversing...
- cancer, anti-inflammatory use and pain. One
class of
these agents are
bryostatin-like compounds,
under investigation as anti-cancer therapy.[citation needed]...
- 1998). "Reversible
phosphorylation of Bcl2
following interleukin 3 or
bryostatin 1 is
mediated by
direct interaction with
protein phosphatase 2A". The...
-
Endobugula sertula,
produces the
bryostatins, a
group of
around twenty bioactive natural products. The
bryostatins are
under investigation for their...
-
founder and chairman of BryoLogyx,
which licensed a
synthetic form of
bryostatin-1 from
Stanford University for the use in
cancer immunotherapy and adjunctive...
