-
Benzothiadiazine is a
bicyclic heterocyclic benzene derivative with the
heterocycle containing two
nitrogens and one sulfur. Some
benzothiadiazine derivatives...
- IDRA-21 is a
positive allosteric modulator of the AMPA
receptor and a
benzothiadiazine derivative. It is a
chiral molecule, with (+)-IDRA-21
being the active...
- but does not have the
chemical properties of a thiazide,
lacking the
benzothiadiazine molecular structure.
Examples include metolazone, chlorthalidone, and...
-
molecules and a
class of
diuretics based on the
chemical structure of
benzothiadiazine. The
thiazide drug
class was
discovered and
developed at
Merck and...
- sulfonamide. It is
related to
analogs of 1,2,4-benzothiadizine-1,1-dioxide (
benzothiadiazine). Such
drugs are
called benzothiadiazides, or
thiazides for short;...
- 1016/0735-1097(89)90002-8. PMID 2685075.
Novello FC,
Sprague JM (1957). "
Benzothiadiazine dioxides as
novel diuretics". J. Am. Chem. Soc. 79 (8): 2028–2029....
- BrandSearch" (PDF). GB 863474, Lund,
Frantz & Godtfredsen, Wagn Ole, "
Benzothiadiazine derivatives and
their preparation",
published 1961-03-22 "LEO Pharma...
- drug)
Identifiers IUPAC name 6-chloro-1,1-dioxo-3,4-dihydro-2H-1,2,4-
benzothiadiazine-7-sulfonamide CAS
Number 58-93-5 Y
PubChem CID 3639 IUPHAR/BPS 4836...
-
Potential Diuretic Agents. I.
Derivatives of 7-Sulfamyl-3,4-dihydro-1,2,4-
benzothiadiazine 1,1-Dioxide".
Journal of the
American Chemical Society. 82 (5): 1132–1135...
- name 3-Benzyl-1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-
benzothiadiazine-7-sulfonamide CAS
Number 73-48-3 Y
PubChem CID 2315 IUPHAR/BPS 7122...
