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Azinomycin B is a
natural product that
contains densely ****embled
functionalities with
potent antitumor activity. It is
isolated from
Streptomyces sahachiroi...
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moiety Neocarzinostatin (as 2-hydroxy-7-methoxy-5-methyl-1-naphthoate)
Azinomycin B (as 3-methoxy-5-methyl-1-naphthoate) Gilman, Henry; St. John, Nina B...
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drugs feature aziridine rings,
including mitomycin C, porfiromycin, and
azinomycin B (carzinophilin). The bond
angles in
aziridine are
approximately 60°...
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isolated from soil in ****an.
Streptomyces griseofuscus produces azinomycin A,
azinomycin B,
bundlin A,
bundlin B,
moldicidin A, physostigmine, fungichromin...
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Accomplished the
first total chemical synthesis of the
novel antitumor agent azinomycin A
Developed the
first synthesis of DNA
containing sulfur-bearing nucleosides...
