-
families of
proteins act as
negative regulators categorized into
either antiapoptotic factors, such as IAPs and Bcl-2
proteins or
prosurvival factors like...
-
electrostatic potential of the
binding groove,
suggest differences in
antiapoptotic activity for the two isoforms. BCL-2 is
localized to the
outer membrane...
- (BCL2-related)".
Kelly GL, Str****er A (March 2020). "Toward
Targeting Antiapoptotic MCL-1 for
Cancer Therapy".
Annual Review of
Cancer Biology. 4: 299–313...
-
apoptosis by
docosahexaenoic acid (22:6n-3): Role of
phosphatidylserine in
antiapoptotic effect".
Journal of
Biological Chemistry. 275 (45): 35215–35223. doi:10...
-
through damaging the ubiquitin-protease system. It also acts as an
antiapoptotic agent preventing programmed cell
death and
controls the
production of...
- RB; Hay, N (2006). "Mitochondrial hexokinases,
novel mediators of the
antiapoptotic effects of
growth factors and Akt". Oncogene. 25 (34): 4683–96. doi:10...
-
These include regulating gene expression, anti-inflammatory effects,
antiapoptotic effects and
protecting endothelial barrier function.: 3162 Treatment...
- Orozco-Suarez S, et al. (November 2008). "Antioxidant,
antiinflammatory and
antiapoptotic effects of
dapsone in a
model of
brain ischemia/reperfusion in rats"...
- is
positively correlated with
tumor progression. Its
glycolytic and
antiapoptotic functions contribute to
proliferation and
protection of
tumor cells...
-
siRNAs to
selectively regulate the
expression of cancer-related genes.
Antiapoptotic proteins, such as
clusterin and survivin, are
often expressed in cancer...