- In the
context of gene regulation:
transactivation is the
increased rate of gene
expression triggered either by
biological processes or by artificial...
- The
transactivation domain or trans-activating
domain (TAD) is a
transcription factor scaffold domain which contains binding sites for
other proteins...
-
expression of anti-inflammatory
proteins in the
nucleus (a
process known as
transactivation) and
represses the
expression of pro-inflammatory
proteins in the cytosol...
-
Intrinsic activity (IA) and
efficacy refer to the
relative ability of a drug-receptor
complex to
produce a
maximum functional response. This must be distinguished...
-
binding sites are
frequently referred to as
activation functions (AFs),
Transactivation domain (TAD) or Trans-activating
domain TAD, not to be
confused with...
-
resulting activated form GR has two prin****l
mechanisms of action,
transactivation and transrepression,
described below. A
direct mechanism of action...
-
Thiazolidinedione ligand dependent transactivation is
responsible for the
majority of anti-diabetic effects....
- promoter.
Localised to the C-terminus,
belongs to the nine
amino acids transactivation domain family, 9aaTAD,
together with Oaf1, Pip2, Pdr1, Pdr3, but also...
-
mediators (transrepression) and
inducing anti-inflammatory
mediators (
transactivation).
Immunosuppressive effects are
mediated by
suppressing dela**** hy****nsitivity...
-
modification through acetylation,
which directly promotes AR-mediated
transactivation,
apoptosis and contact-independent
growth of
prostate cancer cells...
