- steroids,
called steroid-17α-
spirolactones, 17α-spirolactosteroids, or
simply 17α-
spirolactones,
which feature their spirolactone group at the C17α position...
-
evaluating eplerenone. It is also a
steroidal antimineralocorticoid of the
spirolactone group and a
selective aldosterone receptor antagonist (SARA). Eplerenone...
- Phanurane, and Spiroletan, is a
steroidal antimineralocorticoid of the
spirolactone group related to
spironolactone which is used as a
diuretic in Europe...
-
example is spironolactone, a pot****ium-sparing
diuretic of the
steroidal spirolactone group,
which interferes with the
aldosterone receptor (among others)...
- γ-lactone, is a
synthetic steroidal 17α-
spirolactone, or more
simply a
spirolactone. It is an
analogue of
other spirolactones like spironolactone, canrenone,...
- Most antimineralocorticoids,
including spironolactone, are
steroidal spirolactones.
Finerenone is a
nonsteroidal antimineralocorticoid. Mineralocorticoid...
- two forms: an "open"/fluorescent form and a "closed"/nonfluorescent
spirolactone form. The "open" form
dominates in
acidic condition while the "closed"...
- pot****ium
Prorenoic acid (prorenoate)
Prorenone RO-14-9012 RU-26752 SC-5233 (
spirolactone) SC-8109 SC-11927 (CS-1) SC-19886 SC-27169
Spirorenone Spironolactone...
-
Prosthetic group Cytochrome a heme A
Cytochrome b heme B
Cytochrome c heme C (covalently
bound heme b)
Cytochrome d heme D (Heme B with γ-
spirolactone)...
- – with
Pfizer Efidac/24 –
marketed by CIBA
Consumer Pharmaceuticals Spirolactone Viadur –
licensed to
Bayer after approval in 2000, but
marketing was...