-
Siglecs (Sialic acid-binding immunoglobulin-type lectins) are cell
surface proteins that bind
sialic acid. They are
found primarily on the
surface of...
- CD33 or
Siglec-3 (sialic acid
binding Ig-like
lectin 3, SIGLEC3,
SIGLEC-3, gp67, p67) is a
transmembrane receptor expressed on
cells of
myeloid lineage...
- They
found that 9 of the 12
marketed Siglec-Fc
reagents bind to HeLa cells, and two of which,
Siglec-11 and
Siglec-14, had
binding that was vulnerable...
- of the SIGLEC9 gene.
Within the
siglec family of
transmembrane proteins,
Siglec-8
belongs to the CD33-related
siglec subfamily, a
subfamily that has undergone...
-
sixth member of the
SIGLEC family of
receptors to be identified. The
protein has also been
given the CD
designation CD327.
Siglec-6 was
first found to...
- N-terminal IgV-domain, it is also a
member of the
SIGLEC family.
Alternate names for
sialoadhesin include siglec-1 and CD169 (cluster of
differentiation 169)...
-
Crocker PR (Dec 1999). "Identification and
characterization of a
novel siglec,
siglec-7,
expressed by
human natural killer cells and monocytes". J Biol Chem...
- Myelin-****ociated
glycoprotein (MAG,
Siglec-4) is a type 1
transmembrane protein glycoprotein localized in
periaxonal Schwann cell and oligodendrocyte...
- a humanized,
nonfucosylated IgG1
monoclonal antibody that
targets Siglec-8.
Siglec-8 is an
inhibitory receptor present on
eosinophils and mast cells,...
- PMID 9373149.
Cornish AL,
Freeman S,
Forbes G, et al. (1998). "Characterization of
siglec-5, a
novel glycoprotein expressed on
myeloid cells related to CD33". Blood...
