-
Resolvins are
specialized pro-resolving
mediators (SPMs)
derived from omega-3
fatty acids,
primarily eicosapentaenoic acid (EPA) and
docosahexaenoic acid...
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orchestrating the
resolution of inflammation.
Prominent members include the
resolvins and protectins. SPM join the long list of
other physiological agents which...
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prominently the prostaglandins, thromboxanes, leukotrienes, lipoxins,
resolvins, and eoxins. For each subfamily,
there is the
potential to have at least...
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dramatically reduce inflammation through conversion within the body to
resolvins, with
beneficial effects for the
cardiovascular system and arthritis....
- but also many
other agents including the
docosanoids resolvin D1,
resolvin D2, and 17R-
resolvin D1 (see
specialized pro-resolving mediators; oligopeptides...
- anti-inflammatory
specialized proresolving mediators, i.e. lipoxins,
resolvins, maresins, and
neuroprotectins Downregulation of pro-inflammatory molecules...
-
cyclooxygenase 2-derived
resolvin E
series metabolites of the
omega 3
fatty acid,
eicosapentaenoic acid;
certain 15-lipoxygenase-derived
resolvin D
series metabolites...
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proresolving mediators such as the aspirin-triggered lipoxins, aspirin-triggered
resolvins, and aspirin-triggered maresins.
These mediators possess potent anti-inflammatory...
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eicosapentaenoic acid
which is
metabolized to the
Resolvin E's;
docosahexaenoic acid
which is
metabolized to the
resolvin D's, maresins, and neuroprotectins; and...
-
series resolvins (see
Resolvin §
Resolvin Es) and of
docosahexaenoic acid to D
series resolvins (see
Resolvin §
Resolvin Ds).
These resolvins are also...
