-
treatments for
cancer based on
interactions with G-
quadruplexes.
Early evidence for the
formation of G-
quadruplexes in vivo in
cells was
established by isolating...
-
including the
group I intron, the
group II intron, and the ribosome.
Quadruplexes Although the
major groove of
standard A-form RNA is
fairly narrow and...
-
polymerases relative to the DNA
strand in a non-arbitrary manner. G-
quadruplexes, also
known as G4 DNA are
secondary structures found in
nucleic acids...
- the
lowest ionization potential of DNA, were
reported back in 2005 (G-
Quadruplexes at 308 nm) and 2006 (single and
double strands at 266 nm). But this unexpected...
-
Parkinson GN, Lee MP,
Neidle S (June 2002). "Crystal
structure of
parallel quadruplexes from
human telomeric DNA". Nature. 417 (6891): 876–80. Bibcode:2002Natur...
- non-coding
genetic elements,
particularly four-stranded
structures called G-
quadruplexes. His work on the
intervention of
nucleic acid
function using small molecules...
- in
nucleic acid
structure and recognition, and the
research topic of
quadruplexes.
Stephen Neidle was born in
London and
educated at
Hendon County Grammar...
-
those found in vertebrates) to form such G-
quadruplexes that
accommodate it,
rather than a T-loop. G-
quadruplexes present an
obstacle for
enzymes such as...
-
functions remain unclear. G-
quadruplexes are four-stranded DNA
structures formed by guanine-rich sequences. G-
quadruplexes can form in telomeres, oncogene...
- neighbourhood. Most of the
remaining residences are duplexes, triplexes, or
quadruplexes.
Virtually all (97%) the
residences are owner-occupied. The neighbourhood...
