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Pyrrolobenzodiazepines, (PBD) are a
class of
compound that may have
antibiotic or anti-tumor properties. Some
dimeric pyrrolobenzodiazepines are used as...
-
human antibody that
binds to the
protein CD25,
conjugated to a
pyrrolobenzodiazepine dimer toxin. The
experimental drug,
developed by ADC Therapeutics...
- CD33
antibody is
attached to a
highly potent DNA
binding agent, a
pyrrolobenzodiazepine (PBD)
dimer (SGD-1882), via a
proprietary site-specific conjugation...
-
tasks for
computers and
robots without using a
programming language Pyrrolobenzodiazepine, a
medical compound This
disambiguation page
lists articles ****ociated...
- GIST therapy. The
preclinical agent, KTN0182A, is an anti-KIT,
pyrrolobenzodiazepine (PBD)-containing antibody-drug
conjugate which shows anti-tumor...
-
Anthramycin is a
pyrrolobenzodiazepine antibiotic with
antitumor activity.
First derived from the
thermophilic actinomycete Streptomyces refuineus by...
- valine-alanine cleavable,
maleimide linker to a
cytotoxic (anticancer)
pyrrolobenzodiazepine (PBD) dimer.[medical
citation needed] The
antibody binds to CD19...
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Tomaymycin is an
antitumor and
antibiotic pyrrolobenzodiazepine with the
molecular formula C16H20N2O4.
Tomaymycin is
produced by the
bacterium Streptomyces...
-
nonribosomal enterotoxin and was the
first naturally occurring pyrrolobenzodiazepine (PBD) to be ****ociated with
disease in the
human intestine. Previous...
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Chemical structure of "tesirine" (drawn in black). It
consists of a
pyrrolobenzodiazepine type
dimer (top),
which is the
actual anti-cancer agent, a Val–Ala...
