-
which are in ortho-substitution.
Pyrazole is a weak base, with pKb 11.5 (pKa of the
conjugate acid 2.49 at 25 °C).
Pyrazoles are also a
class of compounds...
-
converted to
azines when used in the
preparation of 3,5-disubstituted 1H-
pyrazoles, a
reaction also well
known using hydrazine hydrate. With a transition...
- an amino-ketone and a ketone. Also
reported by
Knorr is a
synthesis of
pyrazoles from 1,3-dicarbonyls and hydrazines, hydrazides, or semibicarbazides....
-
Methylpiperidinopyrazole (MPP) is a synthetic, nonsteroidal, and
highly selective antagonist of ERα that is used in
scientific research to
study the function...
-
applications involve conversion of
hydrazine to
heterocyclic rings such as
pyrazoles and pyridazines.
Examples of
commercialized bioactive hydrazine derivatives...
- Michel; Bentiss,
Fouad (2008). "New one step
synthesis of 3,5-disubstituted
pyrazoles under microwave irradiation and
classical heating".
Journal of Heterocyclic...
- carbamates,
synthetic pyrethroids, neonicotinoids, oxadiazines, and
phenyl pyrazoles.
German ****roach
resistance was
first observed with
chlordane in 1952...
-
undergo condensation. For example,
condensation with
Hydrazine produces pyrazoles while condensation with Urea
provides pyrimidines.
Condensation with two...
-
substrates contain O-H, N-H, S-H bonds,
including alcohols, phenols,
pyrazoles, and thiols. NaH
notably deprotonates carbon acids (i.e., C-H bonds) such...
- annually.
Pyrazolones have been
studied as ligands. Kornis, Gabe I. (2000). "
Pyrazoles, Pyrazolines, and Pyrazolones". Kirk-Othmer
Encyclopedia of
Chemical Technology...