- The
purinosome is a ****tive multi-enzyme
complex that
carries out de novo
purine biosynthesis within the cell. It is
postulated to
include all six of...
-
Benkovic discovered the
first example of a
reversible metabolon, the
purinosome in de novo
purine biosynthesis, that only ****embles in
response to cellular...
-
Pennsylvania State University, USA "On de novo
purine biosynthesis: The
purinosome" 14 96
September 22, 2016
Wolfgang Baumeiste r
Department of Molecular...
- 'signalosomes', 'granules', 'bodies', '****emblies', 'paraspeckles', '
purinosomes', 'inclusions', 'aggregates' or 'factories'.
During this time period...
-
performed metabolomics to
trace how
purines are
synthesized within purinosomes and used
isotope labeling and SIMS
imaging to
directly observe hotspots...
-
contributions to
understanding catalysis and
complex biological machines — the
purinosome and DNA
polymerases —
which demonstrate the
power of
chemistry to solve...
