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Proglucagon is a
protein that is
cleaved from preproglucagon.
Preproglucagon in
humans is
encoded by the GCG gene.
Proglucagon is a
precursor of glucagon...
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deriving from the tissue-specific
posttranslational processing of the
proglucagon peptide. It is
produced and
secreted by
intestinal enteroendocrine L-cells...
- of insulin,
which lowers extracellular glucose. It is
produced from
proglucagon,
encoded by the GCG gene. The
pancreas releases glucagon when the amount...
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synthesis facility. She
arrived at MGH
shortly after Joel
Habener had
cloned proglucagon by
studying anglerfish found in
Boston Harbor.
Mojsov worked on the identification...
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immunoreactivity with glucagon. A half-century later,
Brubaker and
Drucker studied proglucagon gene expression, they
discovered the
function of
enteroglucagon is related...
-
proopiomelanocortin and they act
together to
process proinsulin and
proglucagon in
pancreatic islets. PC1/3 is an
enzyme that
performs the proteolytic...
- GLP-2 is
created by
specific post-translational
proteolytic cleavage of
proglucagon in a
process that also
liberates the
related glucagon-like peptide-1...
-
similar polypeptides (such as GLP1 and GLP2) all come (via PTM) from
proglucagon,
which comes from preproglucagon,
which is the
polypeptide that the GCG...
- the
proglucagon-derived peptides,
including endogenous GLP-1, glucagon-like peptide-2, glucagon, oxyntomodulin,
glicentin and
major proglucagon fragment...
- Habener. Drucker’s
discoveries in
Boston included the
demonstration that
proglucagon could be
cleaved into
multiple smaller glucagon-like peptides, including...
