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Phorbol is a natural, plant-derived
organic compound. It is a
member of the
tigliane family of diterpenes.
Phorbol was
first isolated in 1934 as the hydrolysis...
-
diterpenoid phorbol.
Protein kinase C (PKC) is a
phorbol ester receptor.
Phorbol esters can
stimulate PKC in a
similar way to diglycerides.
Phorbol esters...
-
tetradecanoylphorbol acetate,
tetradecanoyl phorbol acetate, and
phorbol 12-myristate 13-acetate (PMA) is a
diester of
phorbol. It is a
potent tumor promoter often...
-
enzyme phorbol-diester
hydrolase (EC 3.1.1.51)
catalyzes the
reaction phorbol 12,13-dibutanoate + H2O ⇌ {\displaystyle \rightleftharpoons }
phorbol 13-butanoate...
- of the
chemical compound phorbol.Tumor
promotion activity was
traced to
phorbol esters present in
croton oil. Pure
phorbol 12-myristate 13-acetate which...
-
Phorbol 12,13-dibutyrate (PDBu) is a
phorbol ester which is one of the
constituents of
croton oil. As an
activator of
protein kinase C, it is a weak tumor...
- release.
Diacylglycerol can be
mimicked by the tumor-promoting
compounds phorbol esters. In
addition to
activating PKC,
diacylglycerol has a
number of other...
- in the
Euphorbiaceae family. It is a
spurge native to
southern Africa.
Phorbol has been
isolated from the
latex of this
perennial plant.
Wikimedia Commons...
-
structural basis for some
natural chemical compounds such as
phorbol.
Abietane Labdane Ingenane Phorbol esters Tigilanol tiglate "Tigliane", Pubchem, retrieved...
- Pa****axel (Pacific yew)
Paracetamol (acetaminophen)
Phenylacetylrinvanil Phorbol esters (e.g., 4α-PDD)
Piperine (black pepper, long pepper)
Polygodial (Dorrigo...
