-
Salts and
esters of
oxalosuccinic acid are
known as
oxalosuccinates.
Oxalosuccinic acid/
oxalosuccinate is an
unstable 6-carbon
intermediate in the tricarboxylic...
- process,
which involves oxidation of
isocitrate (a
secondary alcohol) to
oxalosuccinate (a ketone),
followed by the
decarboxylation of the
carboxyl group beta...
-
under normal cir****stances
catalyzes the
oxidation of
isocitrate to
oxalosuccinate,
which then
spontaneously decarboxylates to alpha-ketoglutarate, as...
-
cycle include:
pyruvate to acetyl-CoA (see
pyruvate decarboxylation)
oxalosuccinate to α-ketoglutarate α-ketoglutarate to succinyl-CoA. Straight-chain fatty...
- +
oxalosuccinate The 3
substrates of this
enzyme are ATP, 2-oxoglutarate, and HCO3-,
whereas its 3
products are ADP, phosphate, and
oxalosuccinate. This...
- ADP (GDP) Succinyl-CoA NADH + H+ + CO2 CoA NAD+
Citrate H2O cis-Aconitate H2O
Isocitrate NAD(P)+ NAD(P)H + H+
Oxalosuccinate CO2 2-oxoglutarate...
- ADP (GDP) Succinyl-CoA NADH + H+ + CO2 CoA NAD+
Citrate H2O cis-Aconitate H2O
Isocitrate NAD(P)+ NAD(P)H + H+
Oxalosuccinate CO2 2-oxoglutarate...
- for activity.
Unlike EC 1.1.1.42,
isocitrate dehydrogenase (NADP+),
oxalosuccinate cannot be used as a substrate. In eukaryotes,
isocitrate dehydrogenase...
- ADP (GDP) Succinyl-CoA NADH + H+ + CO2 CoA NAD+
Citrate H2O cis-Aconitate H2O
Isocitrate NAD(P)+ NAD(P)H + H+
Oxalosuccinate CO2 2-oxoglutarate...
- ADP (GDP) Succinyl-CoA NADH + H+ + CO2 CoA NAD+
Citrate H2O cis-Aconitate H2O
Isocitrate NAD(P)+ NAD(P)H + H+
Oxalosuccinate CO2 2-oxoglutarate...
