- An
oncomir (also
oncomiR) is a
microRNA (miRNA) that is ****ociated with cancer.
MicroRNAs are
short RNA
molecules about 22
nucleotides in length. Essentially...
- Dishevelled. PTEN is one of the
targets for drug
candidates such as the
oncomiR, MIRN21. The
structure of the core of PTEN (solved by X-ray crystallography...
- in
humans is
encoded by the PDCD4 gene. It is one of the
targets of an
oncomiR, MIRN21. This gene
encodes a
protein localized to the
nucleus in proliferating...
- also have
links with
cancer and
accordingly are
sometimes referred to as "
oncomirs". In
malignant B
cells miRNAs parti****te in
pathways fundamental to B...
-
expression by
downregulating them.
Mutations in such
microRNAs (known as
oncomirs) can lead to
activation of oncogenes.
Antisense messenger RNAs
could theoretically...
-
production and lifespan, and the up-regulation and down-regulation of
oncomirs.
Given their role in presentation, HSPs are
useful as
immunologic adjuvants...
- in
humans is
encoded by the ANP32A gene. It is one of the
targets of an
oncomiR, MIRN21.
Acidic leucine-rich
nuclear phosphoprotein 32
family member A...
-
involved in
tumor invasion and metastasis. It is one of the
targets of an
oncomiR, MIRN21. GRCh38:
Ensembl release 89: ENSG00000122707 – Ensembl, May 2017...
- Li Y, Gu H, Liu MF, Wang ED (Apr 2010). "MicroRNA-155
functions as an
OncomiR in
breast cancer by
targeting the
suppressor of
cytokine signaling 1 gene"...
-
abnormalities in the
heart and
vascular system. It is one of the
targets of an
oncomiR, MIRN21. In
humans mutations of this gene
result in
autosomal dominant...
