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Norpethidine (normeperidine,
pethidine intermediate B) is a 4-phenylpiperidine
derivative that is both a
precursor to, and the
toxic metabolite of, pethidine...
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neurotoxicity of its metabolite,
norpethidine, it is more
toxic than
other opioids—especially
during long-term use. The
norpethidine metabolite was
found to have...
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Diphenoxylate is made by
combining a
precursor of
normethadone with
norpethidine.
Loperamide (Imodium) and
bezitramide are analogs. Like loperamide, it...
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situation significant adverse effects from the
pethidine metabolite norpethidine may occur.
Magnesium sulfate (epsom salts) has been
proposed as a treatment...
- with this syndrome.
Pethidine is
avoided due to the
toxic metabolite norpethidine because of the high
amounts needed to
achieve pain relief. Most reported...
-
Methadone intermediate Moramide intermediate Pethidine intermediate A
Norpethidine (Pethidine
intermediate B)
Pethidinic acid (Pethidine
intermediate C)...
- of
isonipecotic acid, like pethidine, and is
metabolized in part to
norpethidine. Its
potency range is due to
method of ingestion.
figure 20–80 times...
-
significantly greater in
vitro potency compared to desmethylprodine.
Norpethidine PEPAP US 2765314,
Schmidle CJ,
Mansfield RC, "Preparation of Esters"...
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Methylenedioxycyclopropylmethylamphetamine Methylketobemidone Methylphenidate Norpethidine ORG-37684
Piperoxan 2C-E-FLY This set
index page
lists chemical structure...
- (Prepethidine) 1-Methyl-4-phenylpiperidin-4-carbonitril
Pethidine intermediate B (
Norpethidine) Ethyl(4-phenylpiperidin-4-carboxylat)
Pethidine intermediate C (Pethidinic...
