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Motexafin lutetium is a texaphyrin,
marketed as
Antrin by
Pharmacyclics Inc. It is a
photosensitiser for use in
photodynamic therapy to
treat skin conditions...
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Motexafin gadolinium (proposed
tradename Xcytrin) is an
inhibitor of
thioredoxin reductase and
ribonucleotide reductase. It has been
proposed as a possible...
- (INN)
motapizone (INN)
motavizumab (INN)
motesanib (USAN)
motexafin gadolinium (USAN)
motexafin lutetium (USAN)
Motofen motrazepam (INN)
motretinide (INN)...
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formation of
deoxyribonucleotides (building
blocks of DNA).
Examples include:
motexafin gadolinium.
hydroxyurea fludarabine, cladribine, gemcitabine, tezacitabine...
- Ford JM,
Daniels MJ,
Erhardt RJ,
Frazer BH, et al. (January 2006). "
Motexafin-gadolinium
taken up in
vitro by at
least 90% of
glioblastoma cell nuclei"...
-
university to
develop commercial and
medical uses for the molecules.
Motexafin lutetium is a texaphyrin,
marketed as
Antrin by
Pharmacyclics Inc. It...
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treat cancer, infections, and
other diseases. The
drugs hydroxyurea and
Motexafin gadolinium interfere with the
action of this enzyme.
Elledge SJ, Zhou...
-
clinical trials for the
treatment of
cancers include Photofrin, Temoporfin,
Motexafin lutetium,
Palladium bacteriopheophorbide, Purlytin, and Talaporfin. Verteporfin...
-
several types of cancer,
including malignant mesothelioma. For example,
motexafin gadolinium (MGd) is a new
chemotherapeutic agent that
selectively targets...
-
increase cellular ROS
stress level,
either by
direct ROS-generation (e.g.
motexafin gadolinium, elesclomol) or by
agents that
abrogate the
inherent antioxidant...
