- laboratory;
microsomes are not
present in healthy,
living cells.
Rough (containing ribosomes) and
smooth (without ribosomes)
microsomes are made from...
-
minutes in a
suitable medium; this
fraction contains cytosol and
microsomes." The
microsomes component of the S9
fraction contain cytochrome P450 isoforms...
- CYP2B6, and CYP2C9
isoforms to N-demethylation of
ketamine in
human liver microsomes". Drug
Metabolism and Disposition. 30 (7): 853–8. doi:10.1124/dmd.30.7...
- "Cytochrome P450 3A-mediated
metabolism of
buspirone in
human liver microsomes". Drug
Metabolism and Disposition. 33 (4): 500–507. doi:10.1124/dmd.104...
- 8-prenylnaringenin, a
potent phytoestrogen from hops (Humulus lupulus), by
human liver microsomes". Drug
Metabolism and Disposition. 32 (2): 272–279. doi:10.1124/dmd.32...
-
tropoflavin in
human liver microsomes. In
contrast to R7, R13 is
readily hydrolyzed into
tropoflavin in
human liver microsomes. Braegen-02 List of investigational...
-
higher than that of LSD [73–75]. In
incubations of LSD with
human liver microsomes and hepatocytes, 2,3-dihydroxy-LSD
could be
identified [71]. So far, the...
- S(-)-nicotine N1-glucuronide has a
lower Km and
higher Vmax for
liver microsomes than the N(+)-nicotine N1-glucuronide,
suggesting that the body has evolved...
-
adverse events, tolerance,
rebound insomnia, and
daytime alertness.
Microsome studies indicate zolpidem is
metabolized by CYP3A4 (61%) CYP2C9 (22%)...
- urine.
These metabolites are also
found after oxidation with rat
hepatic microsomes in vitro.[citation needed] The C-hydroxylated
metabolites may be considered...