- 5′-
Methylthioadenosine is S-methyl
derivative of the adenosine. It is an
intermediate in the
methylthioadenosine (MTA) cycle, also
known as the methionine...
-
responsible for
polyamine metabolism. In humans, it is
encoded by the
methylthioadenosine phosphorylase (MTAP) gene on
chromosome 9.
Multiple alternatively...
- In enzymology, a
methylthioadenosine nucleosidase (EC 3.2.2.16) is an
enzyme that
catalyzes the
chemical reaction S-methyl-5'-thioadenosine + H2O ⇌ {\displaystyle...
-
methionine from its
downstream products. A
version of the
pathway uses
methylthioadenosine (MTA),
forming the so-called MTA
cycle with its
synthesizing reaction...
-
cogenerates methionine S-adenosyl homocysteine,
releasing methyl radical methylthioadenosine (SMT),
homoalanine radical The
reactions that produce, consume, and...
-
state structures.
Methylthioadenosine nucleosidase are
enzymes that
catalyse the
hydrolytic deadenylation reaction of 5'-
methylthioadenosine and S-adenosylhomocysteine...
-
aminocyclopropanecarboxylate synthase, ACC synthase, and S-adenosyl-L-methionine
methylthioadenosine-lyase. This
enzyme parti****tes in
propanoate metabolism. It employs...
- S-adenosylmethionine. The
latter donates the
equivalent of α-amino-γ-butyrolactone.
Methylthioadenosine is a coproduct.
Homoserine lactones are also a
product of the proteolytic...
- S-adenosyl-L-methionine + tRNA
uridine ⇌ {\displaystyle \rightleftharpoons } 5'-
methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine Thus, the two substrates...
-
Vodnala M,
Ranjbarian F,
Pavlova A, de
Koning HP,
Hofer A (2016). "
Methylthioadenosine Phosphorylase Protects the
Parasite from the
Antitrypanosomal Effect...