Definition of Macrocyclization. Meaning of Macrocyclization. Synonyms of Macrocyclization

- reported for studies on terpenoid macrocycles. The central challenge to macrocyclization is that ring-closing reactions do not favor the formation of large...
- synthesis of the macrolide (+)-a****ilin by an asymmetrically catalyzed macrocyclization of an ω-Alkynal ester". Tetrahedron Letters. 36 (15): 2607–2610. doi:10...
- organic chemistry, the high dilution principle is a strategy for some macrocyclization reactions, i.e. the synthesis of macrocycles. Unlike the synthesis...
- 1074/jbc.M212364200. PMID 12569104. Kopp F, Marahiel MA (August 2007). "Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis". Natural...
- found both in plants and in animals. Cembrenes are biosynthesized by macrocyclization of geranylgeranyl pyrophosphate. Vanderah, David J.; Rutledge, Neal;...
- L-Leu10 (See figure 4). There is no general biochemical solution for macrocyclization of a peptide chain. Isolated tyrocidine (Tyc) TE domains can be used...
- peptide (Figure 6). Elongation by these NRPS modules ultimately leads to macrocyclization and release in which an α-amino group, namely threonine, acts as an...
- permeability. The design of class A peptidomimetics often involves macrocyclization strategies as for example in stapled peptides. This class of peptidomimetics...
- directed syntheses are mostly performed under kinetic control, when the macrocyclization (catenation) reaction is irreversible. More recently, the groups of...
- acyloin condensation can be deplo**** similarly. For larger rings (macrocyclizations) more elaborate methods are required since intramolecular ring closure...