- l-
Kynurenine is a
metabolite of the
amino acid l-tryptophan used in the
production of niacin.
Kynurenine is
synthesized by the
enzyme tryptophan dioxygenase...
- the
kynurenine pathway include tryptophan,
kynurenine,
kynurenic acid,
xanthurenic acid,
quinolinic acid, and 3-hydroxykynurenine. The
kynurenine pathway...
-
kynurenine 3-monooxygenase (EC 1.14.13.9) is an
enzyme that
catalyzes the
chemical reaction L-
kynurenine +
NADPH + H+ + O2 ⇌ 3-hydroxy-L-
kynurenine +...
-
Kynureninase or L-
Kynurenine hydrolase (KYNU) (EC 3.7.1.3) is a PLP
dependent enzyme that
catalyses the
cleavage of
kynurenine (Kyn) into
anthranilic acid...
- In enzymology, a
kynurenine 7,8-hydroxylase (EC 1.14.99.2) is an
enzyme that
catalyzes the
chemical reaction kynurenate + AH2 + O2 ⇌{\displaystyle \rightleftharpoons...
- (TDO) in the liver, are
responsible for the
synthesis of
kynurenine from tryptophan. The
kynurenine pathway of
tryptophan catabolism is
altered in several...
-
apparently named after. It is
formed from L-
kynurenine in a
reaction catalyzed by the
enzyme kynurenine—oxoglutarate transaminase. KYNA has been proposed...
-
biosynthetic precursor to niacin.
Quinolinic acid is a
downstream product of the
kynurenine pathway,
which metabolizes the
amino acid tryptophan. It acts as an NMDA...
-
intermediate in the
catabolism of tryptophan. It is a
formylated derivative of
kynurenine. The
formation of N′-formylkynurenine is
catalyzed by heme dioxygenases...
-
Picolinic acid is a
catabolite of the
amino acid
tryptophan through the
kynurenine pathway. Its
function is unclear, but it has been
implicated in a variety...
