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Kainic acid, or
kainate, is an acid that
naturally occurs in some seaweed.
Kainic acid is a
potent neuroexcitatory amino acid
agonist that acts by activating...
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Kainate receptors, or
kainic acid
receptors (KARs), are
ionotropic receptors that
respond to the
neurotransmitter glutamate. They were
first identified...
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selective agonist for the AMPA receptor, with only
limited effects at the
kainate receptor. It is an
excitotoxic neurotoxin when used in vivo and so is rarely...
- receptors, and
metabotropic glutamate receptors. A
fourth class,
known as
kainate receptors, are
similar in many
respects to AMPA receptors, but much less...
- of the AMPA and
kainate subtypes of the
ionotropic glutamate receptor family, with
selectivity for the GluR5
subtype of the
kainate receptor. It has...
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Glutamate ionotropic receptor kainate type
subunit 2, also
known as
ionotropic glutamate receptor 6 or GluR6, is a
protein that in
humans is
encoded by...
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cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione) is a
competitive AMPA/
kainate receptor antagonist. Its
chemical formula is C9H4N4O4. CNQX is
often used...
- has no
effect on
other glutamate receptors (such as
those for AMPA and
kainate). NMDA
receptors are
particularly important when they
become overactive...
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ionotropic glutamate receptors in the
micromolar range,
including the AMPA and
kainate receptors and, to a
lesser extent, the NMDA receptor. It acts as an antagonist...
- receptors: AMPA and
kainate receptors.
Willardiine analogs have been
developed that have
different binding affinities for the AMPA and
kainate receptors. These...