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Kainic acid, or
kainate, is an acid that
naturally occurs in some seaweed.
Kainic acid is a
potent neuroexcitatory amino acid
agonist that acts by activating...
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Kainate receptors, or
kainic acid
receptors (KARs), are
ionotropic receptors that
respond to the
neurotransmitter glutamate. They were
first identified...
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cyanquixaline (6-cyano-7-nitroquinoxaline-2,3-dione) is a
competitive AMPA/
kainate receptor antagonist. Its
chemical formula is C9H4N4O4. CNQX is
often used...
- receptors, and
metabotropic glutamate receptors. A
fourth class,
known as
kainate receptors, are
similar in many
respects to AMPA receptors, but much less...
- receptors: AMPA and
kainate receptors.
Willardiine analogs have been
developed that have
different binding affinities for the AMPA and
kainate receptors. These...
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receptor antagonist (IC50
values are 10-20, ~ 450 and >> 50 μM for AMPA-,
kainate- and NMDA-induced
responses respectively), orally-active anticonvulsant...
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Glutamate receptor, ionotropic,
kainate 1, also
known as GRIK1, is a
protein that in
humans is
encoded by the GRIK1 gene. This gene
encodes one of the...
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damaged neurons.
Riluzole has also been
reported to
directly inhibit the
kainate and NMDA receptors. The drug has also been
shown to
postsynaptically potentiate...
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selective agonist for the
kainate receptor. This
potent agonist has
nearly 3,000 fold- and 200-fold
selectivity for
kainate receptors over AMPA and NMDA...
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mechanisms of
glutamate receptors. He
described the
existence of
functional kainate receptors (KARs) in
central neurons and
applied single-cell RT-PCR to study...
