- əljʊəˈrɒnɪk/;
abbreviated HA;
conjugate base hyaluronate), also
called hyaluronan, is an anionic,
nonsulfated glycosaminoglycan distributed widely throughout...
-
Hyaluronan synthases (HAS) are membrane-bound
enzymes that use UDP-α-N-acetyl-D-glucosamine and UDP-α-D-glucuronate as
substrates to
produce the glycosaminoglycan...
- it has a high affinity. The
polyanionic form,
commonly referred to as
hyaluronan, is a visco-elastic
polymer found in the
aqueous and
vitreous humour of...
-
matrix interactions with
hyaluronan binding proteins such as hyaluronectin,
glial hyaluronan binding protein,
brain enriched hyaluronan binding protein, collagen...
- that are
produced by
cells within the
joint tissues. The
fluid contains hyaluronan secreted by fibroblast-like
cells in the
synovial membrane,
lubricin (proteoglycan...
-
cellular debris in the
visual field, and hyalocytes,
which turn over the
hyaluronan. The
vitreous humour contains no
blood vessels, and 98–99% of its volume...
-
fluid by
removing wear-and-tear debris. As for the FLS, they
produce hyaluronan, as well as
other extracellular components in the
synovial fluid. The...
-
catalyzing the
hydrolysis of
hyaluronan, a
constituent of the
extracellular matrix,
hyaluronidase lowers the
viscosity of
hyaluronan,
thereby increasing tissue...
-
Hyaluronan-mediated
motility receptor (HMMR), also
known as
RHAMM (Receptor for
Hyaluronan Mediated Motility) is a
protein which in
humans is
encoded by...
- is aggrecan, which, as its name suggests,
forms large aggregates with
hyaluronan and with itself.
These aggregates are
negatively charged and hold water...
