-
metabolize arachidonic acid to 15(S)-hydroperoxyeicosatetraenoic acid (15(S)-
HpETE). This
initial hydroperoxide product is
extremely short-lived in cells:...
-
metabolize 15-
HPETE to
eoxins in a
pathway analogous to (and
presumably using the same
enzymes as used in) the
pathway which metabolizes 5-
HPETE to leukotrienes...
-
arachidonic acid to 15-
HpETE and 12-
HpETE products in an 89 to 11 ratio,
metabolizes arachidonic acid to 15-
HpETE and 12-
HpETE in a 1 to 6 ratio, i.e...
-
hydroperoxy residue (e.g. 5-hydroperooxy-eicosatraenoic acid or 5-
HpETE or 5-
HPETE); H for a
hydroxy residue (e.g. 5-hydroxy-eicosatetraenoic acid or...
-
Arachidonic acid 5-hydroperoxide (5-hydroperoxyeicosatetraenoic acid, 5-
HPETE) is an
intermediate in the
metabolism of
arachidonic acid by the ALOX5 enzyme...
-
Activators 4-Hydroxynonenal 4-Oxo-2-nonenal 5,6-EET 12S-
HpETE 15-Deoxy-Δ12,14-prostaglandin J2 α-Sanshool (ginger,
Sichuan and
melegueta peppers) Acrolein...
- 12(S)-
HpETE and 12(R)-
HpETE or 12(S)-HETE and 12(R)-HETE; the R
stereoisomer predominates in
these mixtures. The
initial 12(S)-
HpETE and 12(R)-
HpETE products...
-
Activators 4-Hydroxynonenal 4-Oxo-2-nonenal 5,6-EET 12S-
HpETE 15-Deoxy-Δ12,14-prostaglandin J2 α-Sanshool (ginger,
Sichuan and
melegueta peppers) Acrolein...
- PPARαTooltip
Peroxisome proliferator-activated
receptor alpha Agonists: 15-HETE 15-
HpETE Aleglitazar Aluminium clofibrate Arachidonic acid
Bezafibrate Chiglitazar...
-
Activators 4-Hydroxynonenal 4-Oxo-2-nonenal 5,6-EET 12S-
HpETE 15-Deoxy-Δ12,14-prostaglandin J2 α-Sanshool (ginger,
Sichuan and
melegueta peppers) Acrolein...