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Glypicans constitute one of the two
major families of
heparan sulfate proteoglycans, with the
other major family being syndecans. Six
glypicans have been...
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subunit has a size of ~40 kDa and the C-terminal
subunit is ~30 kDa. Six
glypicans (GPC1-6) have been
identified in mammals. Cell
surface heparan sulfate...
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Glypican-6 is a
protein that in
humans is
encoded by the GPC6 gene. The
glypicans comprise a
family of glycosylphosphatidylinositol-anc****d
heparan sulfate...
- 4518. PMID 9070915. "Entrez Gene: GPC5
glypican 5". De Cat B,
David G (2001). "Developmental
roles of the
glypicans". Semin. Cell Dev. Biol. 12 (2): 117–25...
- Y,
Sasisekharan R,
Cantley L,
Sukhatme VP (April 2001). "Cell
surface glypicans are low-affinity
endostatin receptors" (PDF).
Molecular Cell. 7 (4): 811–22...
- R,
Karihaloo A,
Tsiokas L, Chan B, et al. (April 2001). "Cell
surface glypicans are low-affinity
endostatin receptors".
Molecular Cell. 7 (4): 811–822...
- PMC 3031711. PMID 21112773. Li N, Gao W,
Zhang YF, Ho M (November 2018). "
Glypicans as
Cancer Therapeutic Targets".
Trends in Cancer. 4 (11): 741–754. doi:10...
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expressed doubt regarding the
involvement of PTEN or GPC3,
which codes for
glypican 3 and may play a role in
regulating cell
division and
growth regulation...
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exploring T
cells engineered with
chimeric antigen receptors (CARs)
targeting glypican-3 (GPC3), such as GAP T cells,
showing potential in
addressing GPC3-positive...
- PMC 4362340. PMID 26015949. Li, Nan; Ho, Mitc**** (2022). "Development of
Glypican-2
Targeting Single-Domain
Antibody CAR T
Cells for Neuroblastoma". Single-Domain...
