- cell-depleting agent. Third-generation anti-CD20s such as
obinutuzumab have a
glycoengineered Fc
fragment (Fc) with
enhanced binding to Fc
gamma receptors, which...
- PMC 4340844. PMID 25578468.
Sinclair AM,
Elliott S (August 2005). "
Glycoengineering: the
effect of
glycosylation on the
properties of
therapeutic proteins"...
-
Laboratory for the
Reduction of Coal-fired
Pollutants Emission National Glycoengineering Research Center Key
Laboratory for
Colloid and
Interface Chemistry...
- 2003). "Enhancement of
therapeutic protein in vivo
activities through glycoengineering".
Nature Biotechnology. 21 (4): 414–21. doi:10.1038/nbt799. PMID 12612588...
-
modified O-glycans,
using methods such as
direct oxidation and
metabolic glycoengineering. The
modified O-glycans
facilitate mucin conjugation with
other molecules...
- the
effectiveness of SAMs in
human body. Currently,
advancements in
glycoengineering have made use of SAM-decorated nanoparticles, SAM-decorated polymers...
-
worked with
Robert Langer to
found Mimeon based on work by
Langer on
glycoengineering; the
company changed its name to
Momenta Pharmaceuticals the next year...
-
incorporated in
glycoproteins of
human mesenchymal stromal cells by
metabolic glycoengineering. Jürgen Mut,
Stephan Altmann,
Sabine Reising,
Jutta Meißner-Weigl,...
- that
focuses on
developing new
pharmaceuticals through glycomics and
glycoengineering.
Although research in this
field presents many difficulties, translational...
-
Haemophilus influenzae HMW1A adhesin. N-glycosyltransferases may be a
novel glycoengineering tool,
considering that they do not
require a
lipid carrier to perform...
